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  • Habich M, Salscheider SL, Murschall LM, Hoehne MN, Fischer M, Schorn F, Petrungaro C, Ali M, Erdogan AJ, Abou-Eid S, Kashkar H, Dengjel J, Riemer J. (2019) Vectorial Import via a Metastable Disulfide-Linked Complex Allows for a Quality Control Step and Import by the Mitochondrial Disulfide Relay. Cell reports 2019 Jan 15;26(3):759-774.e5. doi: 10.1016/j.celrep.2018.12.092.


  • Meyer AJ, Riemer J, Rouhier N. (2018) Oxidative protein folding: state-of-the-art and current avenues of research in plants. New Phytol. doi: 10.1111/nph.15436

  • Habich M, Salscheider SL, Riemer J. (2018) Cysteine residues in mitochondrial intermembrane space proteins: more than just import. British Journal of Pharmacology. doi: 10.1111/bph.14480.

  • Erdogan AJ, Ali M, Habich M, Salscheider SL, Schu L, Petrungaro C, Thomas LW, Ashcroft M, Leichert LI, Roma LP, Riemer J. (2018) The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo. Redox Biol. doi: 10.1016/j.redox.2018.03.014.




  • Appenzeller-Herzog C, Bánhegyi G, Bogeski I, Davies KJ, Delaunay-Moisan A, Forman HJ, Görlach A, Kietzmann T, Laurindo F, Margittai E, Meyer AJ, Riemer J, Rützler M, Simmen T, Sitia R, Toledano MB, Touw IP. (2016) Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. Free Radic Biol Med. 2016 May;94:157-60



  • Petrungaro C, Zimmermann KM, Küttner V, Fischer M, Dengjel J, Bogeski I, Riemer J. (2015) The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake. Cell Metab. 2015 Oct 6;22(4):721-33

  • Kojer K, Peleh V, Calabrese G, Herrmann JM, Riemer J. (2015) Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial IMS. Mol Biol Cell. 2015 Jan 15;26(2):195-204


  • Longen S, Woellhaf MW, Petrungaro C, Riemer J, Herrmann JM. (2014) The Disulfide Relay of the Intermembrane Space Oxidizes the Ribosomal Subunit Mrp10 on Its Transit into the Mitochondrial Matrix. Dev Cell. 2014 Jan 13;28(1):30-42


  • Fischer M, Riemer J. (2013) The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond. Int J Cell Biol. 2013;2013:742923
  • Suzuki Y, Ali M, Fischer M, Riemer J. (2013) Human copper chaperone for superoxide dismutase 1 mediates its own oxidation-dependent import into mitochondria. Nat Commun. 2013 Sep 12;4:2430
  • Hoffmann C, Plocharski B, Haferkamp I, Leroch M, Ewald R, Bauwe H, Riemer J, Herrmann JM, Neuhaus HE. (2013) From endoplasmic reticulum to mitochondria: absence of the Arabidopsis ATP antiporter endoplasmic reticulum adenylate transporter1 perturbs photorespiration. Plant Cell. 2013 Jul;25(7):2647-60
  • Fischer M, Horn S, Belkacemi A, Kojer K, Petrungaro C, Habich M, Ali M, Küttner V, Bien M, Kauff F, Dengjel J, Herrmann JM, Riemer J. (2013) Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. Mol Biol Cell. 2013 Jul;24(14):2160-2170
  • Morgan B, Ezeriņa D, Amoako TN, Riemer J, Seedorf M, Dick TP. (2013) Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis. Nat Chem Biol. 2013 Feb;9(2):119-25
  • Eckers E, Petrungaro C, Gross D, Riemer J, Hell K, Deponte M. (2013) Divergent molecular evolution of the mitochondrial sulfhydryl:cytochrome c oxidoreductase Erv in opisthokonts and parasitic protists. J Biol Chem. 2013 Jan 25;288(4):2676-88



  • Klöppel C, Suzuki S, Kojer K, Petrungaro C, Longen S, Fiedler S, Keller S, Riemer J (2011). Mia40-dependent oxidation of cysteines in Domain I of Ccs1 controls its distribution between mitochondria and the cytosol. Mol Biol Cell, 22(20):3749-57
  • Riemer J, Fischer M, Herrmann JM (2011). Oxidation-driven protein import into mitochondria: Insights and blind spots. Biochim Biophys Acta, 1808(3):981-9.
  • Bonn F, Tatsuta T, Petrungaro C, Riemer J, Langer T (2011). Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. EMBO J, 30(13):2545-56.
  • Riemer J, Hansen HG, Appenzeller-Herzog C, Johansson L, Ellgaard L (2011). Identification of the PDI-Family Member ERp90 as an Interaction Partner of ERFAD. PLoS One, 16;6(2):e17037


  • Klöppel C, Michels C, Zimmer J, Herrmann JM, Riemer J (2010). In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress. Biochem Biophys Res Comm, Dec 3;403(1):114-9.
  • Appenzeller-Herzog C, Riemer J, Zito E, Chin KT, Ron D, Spiess M, Ellgaard L (2010). Disulfide production by Ero1α–PDI relay is rapid and effectively regulated. EMBO J, Oct 6;29(19):3318-29.
  • Herrmann JM and Riemer J (2010). The Intermembrane Space of Mitochondondria. Antiox Redox Signal , April, 1
  • Herrmann JM and Riemer J (2010). Oxidation and reduction of cysteines in the intermembrane space of mitochondria: Multiple facets of redox-control. Antiox Redox Signal, May, 24
  • Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A. (2010) A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One. May 11;5(5):e10565.
  • Bien M, Longen S, Wagener N, Chwalla I, Herrmann JM, Riemer J (2010). Mitochondrial Disulfide Bond Formation Is Driven by Intersubunit Electron Transfer in Erv1 and Proofread by Glutathione. Mol. Cell, 37(4):516-528.


  • Riemer J, Bulleid N, Herrmann JM (2009). Disulfide Formation in the ER and Mitochondria: Two Solutions to a Common Process. Science 324(5932):1284-7
  • Longen S, Bien M, Bihlmaier K, Kloeppel C, Kauff F, Hammermeister M, Westermann B, Herrmann JM and Riemer J (2009). Systematic analysis of the twin Cx9C protein family. J Mol Biol. 393(2), 356-68
  • Riemer J, Appenzeller-Herzog C, Johansson L, Bodenmiller B, Hartmann-Petersen R and Ellgaard L. (2009). A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc Nat Acad Sci.106, 14831-14836
  • Roth D, Lynes E, Riemer J, Hansen HG, Althaus N, Simmen T, Ellgaard L (2009). A di-arginine motif contributes to the ER-localization of the type I transmembrane ER oxidoreductase TMX4. Biochem J., 425(1):195-205.


  • Appenzeller-Herzog C, Riemer J, Christensen B, Sørensen E and Ellgaard L (2008). A Novel Disulfide Switch Mechanism in Ero1alpha Balances ER Oxidation in Human Cells. EMBO J. 27, 2977-87


  • Minich T, Riemer J, Schulz JB, Wielinga P, Wijnholds J, Dringen R. (2006). The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes. J. Neurochem., 97, 373-84


  • Riemer J, Hoepken HH, Czerwinska H, Robinson SR, Dringen R. (2004). Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal. Biochem., 331, 370-5.



  • Bader MW, Hiniker A, Regeimbal J, Goldstone D, Haebel PW, Riemer J, Metcalf P, Bardwell JC (2001). Turning a disulfide isomerase into an oxidase: DsbC mutants that imitate DsbA. EMBO J., 20, 1555-62.